For researchers
For academic, pharmaceutical, and biotech researchers, we offer two services (pdf description):
knomeBASE is a compute-intensive informatics service that transforms human genome sequence data into a format optimized for fast interpretation. Designed to help geneticists identify the variants, genes, and pathways that govern human disease and drug response, knomeBASE has two components:
Informatics: knomeBASE standardizes, annotates, compares, and distills raw sequence data—addressing the primary informatics challenges that often bottleneck the process of interpreting multiple genomes.
Tool kit: knomeBASE clients receive easy-to-use genome interpretation applications, libraries, and scripts that enable flexible querying, rapid hypothesis testing, data visualization, and custom software development.
knomeDISCOVERY is a complete genome interpretation solution for researchers. It includes whole genome sequencing, project-driven curation, sophisticated informatics, and in-depth interpretation by Knome’s team of experienced geneticists. knomeDISCOVERY is for researchers who seek to outsource the bioinformatics and genetics needed for whole genome studies of human disease or drug response.
For clinics
Our platform group provides clinics with large-scale, enterprise-wide genome interpretation systems that 1) manage whole genome sequence data; 2) help physicians interpret genomes in order to inform preventative, diagnostic, and treatment decisions; and 3) help medical researchers identify the causal variants that govern the phenotype of interest.
We are working with leading institutions to incorporate genomics into clinical care. These relationships take the form of long-term efforts that result in highly integrated, locally installed versions of our automated informatics engine, heavily curated knowledge databases, research applications, and patient care (physician-facing) applications.
